Corporate social responsibility has become a hot topic in recent years in mainland China. However, different religious brings to different emphases for business owners in the course of implementation, and different responsibilities, the degree of fulfillment of responsibility also varies. In this paper, takes private business owners of mainland China as the research object, choose the main religion of Christianity, Buddhism and Confucianism in mainland for the study, based on elaborating on different religious thought distillation, discussed and analyzed the influence of Christianity, Buddhism and Confucianism on social responsibility to business owners, with a view of giving a reasonable explanation for different behavior of business owners during the process of fulfilling corporate social responsibility.