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荷爾蒙補充治療致靜脈栓塞之檢視

摘要


停經後,荷爾蒙補充治療可以改善停經後的血管症狀、舒緩生殖泌尿道之不適,但也可能增加靜脈栓塞之風險,此與賀爾蒙之種類、劑量、使用方式(如口服或經皮膚使用)所有不同。並需考慮使用者的年齡和體重。當懷疑有靜脈栓塞時,須縝密檢查、確定並治療之。

參考文獻


Beyer-Westendorf J, Bauersachs R, Hach-wenderle V, et al. Sex hormones and venous thromboembolism-from contraception to hoemone replacement therapy. Vasa 2018;47:441-50.
Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 2002;288:321-33.
Anderson GL, Limacher M, Assaf AR, et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA 2004;291:1701-12.
Sweetland S, Beral V, Balkwill A, et al. Venous thromboembolism risk in relation to use of different types of postmenopausal hormone therapy in a large prospective study. J Thromb Haemost 2012;10:2277-86.
Hulley S, Grady D, Bush T, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. JAMA 1998;280:605-13.

被引用紀錄


郝立智、簡崇仁、范麒惠、陳昆祥、林育弘、鄭智仁、吳明瑞、潘潔慧、黃偉輔、楊純宜(2023)。原發性卵巢功能不全的治療建議臨床醫學月刊92(1),467-474。https://doi.org/10.6666/ClinMed.202307_92(1).0078
郝立智、張雅椅、范麒惠、吳鈴鳳、陳麗幸、吳明瑞、潘潔慧、蔡宗憲、陳家禎、楊純宜、簡崇仁、吳志南(2022)。停經後婦女的荷爾蒙補充治療建議臨床醫學月刊89(4),257-265。https://doi.org/10.6666/ClinMed.202204_89(4).0042

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