Acute hemorrhage leading to acute hypovolomic shock is a medical emergency carrying high mortality. It therefore requires prompt and effective treatment. We reported a case of lung tumor receiving lobectomy at our hospital. Repeated internal bleeding due to subclavian artery perforation occurred three times within three weeks after the surgery. During the period of resuscitation, the patient received emergently massive blood transfusion. Some complications of massive blood transfusion were noted later. A total of 89 units of whole blood, 34 units of fresh frozen plasma and 28 units of platelet was given.