Prostate cancer was one of the most commonly cancers in elderly male population, and was easy to be misdiagnosed as joint pain treatment, incurable, detailed examination before the diagnosis of prostate cancer bone metastasis. This case is due to the lower back pain after the diagnosis, in addition to receiving weste medicine hormone therapy, with the TCM six syndrome differentiation diagnosis of less yin heating clamping disease, with the prescription of the nine flavor baicalin soup, as well as Guilin ancient typhoid miscellaneous diseases on the wind evil by the kidney chaihuguizhi Tonga reduced. We provided a good clinical evidence of bone metastasis of prostate cancer with integrated medicine.