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  • 期刊

Distribution of Distant Metastases in Patients with Advanced Adenocarcinoma of the Prostate

攝護腺癌患者遠端轉移部位分析

摘要


本研究共分析154例有遠端轉移的攝護腺癌患者,其中以骨骼最常被侵犯約佔77%;第二位則是淋巴結(36%)。在118位骨骼轉移病患身上共有370處轉移病灶;其中僅48在放射線骨骼攝影中可以發現病灶;73%的病灶是成骨性(Osteoblastic),10%是溶骨性(Osteolytic),17%為混合型。依解剖部位分以脊椎最常見,其次分別骨腔、肋骨及胸骨。和其他惡性腫瘤大不相同的是只是有少數病患侵犯肺部及肝臟。兩例病患轉移至陰莖海棉體;五位患者僅有單一病灶轉移,分別是肋骨、薦椎、頸椎、坐骨及肺部。

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並列摘要


A retrospective analysis was conducted in 154 consecutive cases with advanced prostatic cancer. Bone was the most frequent site of involvement (77%), followed by lymph nodes (36%). A total of 370 skeletal lesions were noted, using radionuclide bone scan in 118 patients. However, only 48 patients had had evidence of bony destruction by radiographic bone survey; of these, 73% were osteoblastic, 10% were osteolytic, and 17% were mixed osteoblastic and osteolytic lesions. The spine was the most common site of metatases followedby pelvis, ribs/sternum. Two patients had metastases to the penis. Five cases had solitary metastatic lesions, involving rib, sacrum, cervical spine, ischium and lung.

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