Patient/physician relations in Taiwan are greatly influenced by traditional Chinese, contemporary western, and colonial medical systems, as well as by sociocultural perceptions of health and illness. This study analyzed letters of complaint and encouragement and the medical experiences of hospital visitors, patients, and primary care givers to understand (1) how patients express their uncertainties when encountered with physicians, and (2) what actions or procedures can substantially reduce the uncertainties of patients and their families. One thousand nine hundred and forty-one letters and 14 in-depth interviews are analyzed. Finally, the importance of medical literacy is discussed under the framework of Taiwanese physician/patient relations. Through these letters and interviews, Taiwanese patients expressed their uncertainties by asking questions of their physicians, requesting various health checks, and complaining about their health problems to medical staff in a repetitive manner. Patients expect their physicians to notice or reduce their uncertainties by answering questions, sharing medical plans or medical knowledge, and intervening positively and energetically with medical action.