- 期刊
- OpenAccess
Sodium-Glucose Transporter
摘要
Glucose enters different tissues and cells in different ways. In intestinal and kidney tubular cells, sodium-glucose transporter is commonly employed for effective utilization of glucose. When blood glucose level exceeds a certain threshold, renal tubular sodium-glucose transporter gene becomes activated. Sodium-glucose transporter action is inhibited and glucosuria appears. Together with angiotensin II and epidermal growth factor, sodium-glucose transporter is also implicated in the pathogenesis of renal disease. Newly developed sodium-glucose transporter inhibitors may help to reduce the reabsorption of glucose and achieve weight reduction by causing the loss of fuel energy. In this paper, putative relationships between sodium-glucose transporter, blood glucose, angiotensin II, and epidermal growth factor are briefly summarized.
延伸閱讀
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