Why are some firms more successful at introducing radical product innovations than others? Following Schumpeter (1942), many researchers have suggested that firm size is the key organizational predictor of radical product innovation. This article provide an alternate view and argue that one key variable that differentiates rums with strong product innovation records from others is the firms' willingness to cannibalize their own investments. This article identified three organizational factors that drive a firm's willingness to cannibalize. Results from a survey of five high-tech firms tend to support the alternate view that willingness to cannibalize is a more powerful driver of radical product innovation than firm size is. These results suggest a need to reconsider conventional wisdom on firm size, cannibalization, and organizational synergy. Besides, we explore the relationship between product innovation and product innovation performance. Finally, we also discuss the mediating effect of product life cycle on the relationship between radical product innovation and product innovation performance.