Being a teacher is a very stressful work. Researches indicated that it may be able to help teachers to face their working problems if effective coping strategies in resilience or releasing stress are provided. It has been years to apply music therapy for relaxation. However, there were limited researches and applications related to topics of teacher's burnout and stress. Due to the concept of whole person spread, music therapy recently has gained much attention in Taiwan. Through the point of view of physical and psychological responses, more information about the application of music therapy on burnout and stress of special education teachers will be discussed in this article.