With the rapid development of society and economy and the improvement of people's overall living standards, medicines, as special commodities related to people's life and health, have attracted more and more attention from the general public for their criticality, effectiveness, safety, and stability. Safety issues have become a common concern of government drug regulatory authorities and drug manufacturers. The effectiveness of the pharmaceutical process is the key to ensuring the quality of medicines. Under the background of the development and application of modern technology, it has become a general trend to use advanced technology and equipment to participate in the pharmaceutical process to ensure the quality of pharmaceutical production. Among them, PLC is a very advanced and intelligent auxiliary technology. The PLC system can guide and monitor the whole process of pharmaceuticals, significantly improving the quality and efficiency of the pharmaceutical industry.