【論文摘要】Prevalence of Coronary Artery Disease among Young Adults (<40 Years Old) who Underwent Coronary Angiography in a Single Level III Private Hospital

Maria Grethel Dimalala ； Karen De Leon ； Karen Miralles ； Rosemarie Ramirez-Ragasa

《海峽循環醫學雜誌》 1卷2S期 (2019/09) Pp. 127-127

https://doi.org/10.6907/SCJ.201909/SP_1(2).0102

摘要

Background/Synopsis: Historically, coronary artery disease (CAD) and acute coronary syndrome (ACS) manifests clinically in middle and older age groups. In recent years, however, younger men and women have increasingly been affected. Very little information exists regarding prevalence of CAD among young adults (＜40 years old) who underwent coronary angiography in the local setting. Objectives/Purpose: We determined the prevalence of CAD among young adult patients (＜40 years old) who underwent coronary angiography in a single, level III private hospital from June 1, 2009 to July 31, 2018. We also determined their demographic and clinical profile, angiographic findings, treatment interventions done and in-hospital outcomes. Methods/Results: We reviewed charts of patients who underwent coronary angiogram from June 2009 to July 2018. The demographic data, clinical presentation, angiographic findings, treatment interventions and in-hospital outcomes were collected . A total of 150 patients were included in the study. The mean age was 34.54 ± 3.82 years and 80% were males. The most common risk factors were hypertension, diabetes mellitus, dyslipidemia, overweight and smoking history. 32% of the patients presented with ACS with 51% presenting as STEMI. The prevalence of CAD (obstructive and non-obstructive) was 59%. 48% of patients had obstructive CAD in which 53% had single vessel disease with majority involving the left anterior descending artery (LAD). Majority of patients (79%) with obstructive CAD underwent percutaneous coronary intervention (PCI). In-hospitality mortality is low at 2%. Conclusion: The prevalence of CAD among young adult patients who underwent coronary angiography at a single, level III private hospital in the Philippines was lower compared to other Asian countries. They were mostly males, smoker and are overweight. They have classic risk factors such as hypertension, diabetes mellitus and dyslipidemia. One third of patients presented with ACS, particularly STEMI. The most common angiographic finding is a single vessel disease involving the LAD. Majority of patients diagnosed with obstructive CAD underwent PCI and had good in-hospital outcomes.