Effects of green tea on Escherichia coli as a uropathogen

Afsaneh Noormandi ； Fatemeh Dabaghzadeh

《Journal of Traditional and Complementary Medicine》 5卷1期 (2015/01) Pp. 15-20

https://doi.org/10.1016/j.jtcme.2014.10.005

摘要

Escherichia coli is the most common cause of urinary tract infections. The development of antibiotic resistance in E. coli is an important problem. Finding alternative antimicrobial agents from plant extracts has received growing interest. Camellia sinensis is a safe, nontoxic, cheap beverage that has been reported to have antimicrobial effects against various pathogenic bacteria including E. coli. Polyphenolic components of green tea (綠茶lǜ chá) have antibacterial activity. Catechins also have synergistic effect with antibiotics such as chloramphenicol, amoxicillin, sulfamethoxazole, azithromycin, levofloxacin, gentamycin, methicillin, naldixic acid, and, especially ciprofloxacin. In this review, all experimental studies that evaluated the effect of green tea on E. coli were collected. Data from in vitro studies on the antimicrobial effects of green tea are promising, but human data are currently lacking. In vivo studies on antibacterial effects of green tea and evaluating the efficacy of its catechins in the treatment of urinary tract infection are needed.

關鍵字

anti-infective agents ； Camellia sinensis ； catechin ； Escherichia coli ； urinary tract infection

參考文獻

Chomarat M. Resistance of bacteria in urinary tract infections. Int J Antimicrob Agents. 2000;16:483-487.

Foxman B. Recurring urinary tract infection: incidence and risk factors. Am J Public Health. 1990;80:331-333.

Reygaert W, Jusufi I. Green tea as an effective antimicrobial for urinary tract infections caused by. Escherichia coli. Front Microbiol. 2013;4:163.

Tariq A, Reyaz A. Camellia sinensis leaves a new treatment against urinary tract infection caused by Pseudomonas fluorescens and Serratia sp. Int J Pharm Sci Res. 2013;4:1546-1550.

Naber KG. Treatment options for acute uncomplicated cystitis in adults. J Antimicrob Chemother. 2000;46(suppl 1):23-27.