Port lifting equipment - field bridges, shore bridge container cranes are important tools for port transportation. With the development of large-scale, lightweight, high-speed and heavy-duty cranes, the dynamic design method based on dynamic load coefficient can no longer meet the design of large-scale port cranes. In this paper, considering the existence of crane track irregularity, the power spectrum of the three major trunk lines of China Railway is used, and the numerical simulation of the crane track irregularity is carried out by the method. After considering the track irregularity, the influence of different speeds and accelerations on the dynamic response of the load-bearing beam under the action of swinging heavy objects.