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Ultrasound-aided Follow-up of Patients with Hashimoto's Thyroiditis and Accompanying Nodules for Papillary Thyroid Carcinoma

摘要


Objectives: To monitor the natural course of thyroid nodules in patients with Hashimoto's thyroiditis with ultrasound during follow-up. Methods: The clinical data about the 192 patients who were treated for HT at the First Affiliated Hospital of Jinan University from January 2017 to December 2019 were collected. There were 89 patients with accompanying nodules. All the patients underwent systematic ultrasound examinations. Ultrasonography (US) was performed again after treatment and the results were compared with those found before. Results: At initial diagnosis, 14 nodules (14.43%) were diagnosed as papillary thyroid carcinoma (PTC) with fine-needle aspiration biopsy (FNAB). After a follow-up period of 6 to 18 months, 22 new nodules were observed, and size increase was found in 8 nodules. Nine nodules were confirmed as PTC with FNAB. The proportion of TI-RADS 4 and 5 at initial diagnosis was similar to that at the end of follow-up (62.3% vs 64.9%, P > 0.05). The incidence of PTC was slightly higher during follow-up than that at initial diagnosis (20.2% vs 14.4%), however, the difference was not statistically significant (P > 0.05). Conclusion: The prevalence of PTC in patients with HT is relatively higher than that in the general population. US can help observe patients with HT closely for new growths of PTC during follow-up.

參考文獻


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