Study on Toxicity of DEHP to Organism and Exposition of Environmental Pollution

Zhigang Zhang ； Xianling Zhou

《International Core Journal of Engineering》 8卷6期 (2022/06) Pp. 208-216

https://doi.org/10.6919/ICJE.202206_8(6).0030

摘要

Bis (2-ethylhexyl phthalate) (DEHP) is a widely used plasticizer. The toxicity of bis (2-ethylhexyl) phthalate was described in this paper. It has been found that it has reproductive toxicity, neurotoxicity, nephrotoxicity, endocrine toxicity and cardiotoxicity. It is mainly exposed to the environment, resulting in air, water, soil and other pollution. This paper mainly studies its toxicity to the body, and understand its pollution to the environment, so that we can prevent, reduce the intake of the body.

關鍵字

DEHP ； Virulence ； Pollution

參考文獻

Kamrin MA. Phthalate risks, phthalate regulation, and public health: a review[J]. J Toxicol Environ Health B Crit Rev, 2009,12(2):157-174.

Frye CA, et al. Endocrine disrupters: a review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems[J]. Neuroendocrinol, 2012.24(1):144-59.

Ankley GT, Bencic DC, Breen MS, et al. Endocrine disrupting chemicals in fish; Developing exposure indicators and predictive models of effects based on mechanism of action[J]. AQUATIC TOXICOLOGY, 2009,92(3):168-178.

Schoeters G, Den Hood E, Dhooge W, et al. Endocrine disruptors and abnormalities of pubertal development [J]. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2008,102(2):168-175.

Huang H, Zhang X, Chen T, et al. Biodegradation of Structurally Diverse Phthalate Esters by a Newly Identified Esterase with Catalytic Activity toward Di(2-ethylhexyl) Phthalate[J]. J Agric Food Chem, 2019, 67(31): 8548-8558.