In order to explore the damage problem in the use of university chairs, chairs in the public teaching building in Henan university of Science and Technology was chosen as the prototype. Firstly, the mechanical model of it was established and its static analysis was carried out. Then the finite element model was established. Based on the theory of the suitable isobaric distribution of ischium and thigh body pressure under different sitting posture, considering the different loading in the actual process of using, 16 working conditions were statically analyzed. The position of maximum deformation and maximum stress were obtained. As a result, based on the position of maximum stress, the steel frame and metal baffle were chosen to be cyclically loaded to perform fatigue analysis. The maximum equivalent stress is at the intersection of the steel frame and the connecting shaft when chairs are subjected to the three loads: load on the front end of the seat, load on the middle of the seat, load on the rear end of the seat. The fatigue life of the steel frame at the position of maximum stress is the shortest, only 18906 cycles. When the load is leaning against the backboard, the position of the maximum equivalent stress is at the metal baffle. And the value of maximum average stress of the model with a tableboard is larger than it without. When the metal baffle is cyclically loaded, the calculation result of the fatigue life of the finite element model with a tableboard is 82.24% larger than that without.