Innovation-driven is the cornerstone of high-quality development, and innovation for development has gradually become a social consensus. Building an excellent innovation ecosystem is the right thing to achieve high-quality development. Through combing domestic and foreign literature and theoretical foundation, on the basis of analyzing the components of manufacturing innovation ecosystem, we analyze the mechanism of high quality development of manufacturing industry, which is innovation-driven being the development strategy, comprehensive innovation being the means to achieve, and innovation ecosystem being the role platform to promote high quality development of manufacturing industry through achieving all-round innovation.