The molds of plastics processing course and its curriculum design is the core course for students majoring in polymer material and engineering. This course covers a wide range, and the mold structure, technological process and technological parameters are complicated, which makes it difficult for students to understand. This project aims to cultivate students' perceptual understanding and improve the quality of teaching by means of realia, virtual simulation and reformed experimental teaching. In the whole course teaching, including classroom theory teaching and practice teaching, through the mold realia, plastic products, multimedia animation and virtual simulation experiment, to deepen students' basic understanding of the mold. Students' perceptual knowledge of the course rises to a rational understanding, which is finally applied in course design, graduation design practice and even employment practice. At the same time, teachers can constantly improve their teaching skills and research skills in the whole research project. In general, the teaching method has played a positive role in the teaching quality and discipline construction of this specialty, and has obviously promoted the teaching level of professional teachers.