To do a good job in college students' innovation and entrepreneurship is an important measure to serve the national strategic deployment of "mass entrepreneurship and innovation" and an important breakthrough to further improve the quality of innovation and entrepreneurship talent training. This paper takes the innovation and entrepreneurship education of Wenzhou Polytechnic as an example to analyze the deficiencies under the background of "Double High Plan" and optimize the countermeasures in the curriculum system, teaching staff, incubation base and policy environment, so as to cultivate high‐quality technical and skilled talents and serve the economic and social development of Wenzhou.