In recent years, China has gradually increased the development process of innovation and entrepreneurship education in colleges, and achieved certain results. However, from the perspective of the current development of professional education in colleges, there is a phenomenon that the degree of correlation between innovation and entrepreneurship education is not high. According to the development trend of higher education reform in China, the curriculum system of entrepreneurship education and professional education in colleges inevitably presents the trend of mutual integration. Therefore, in order to achieve the integrated development of the curriculum system between the two, it is necessary to constantly strengthen the teaching concept, integrate the curriculum structure and promote the entrepreneurial and professional training work, so as to promote the organic integration between the two, so as to cultivate high-quality talents.