The important force to maintain the sustainable development of institutions is the professional and technical personnel in the grassroots institutions. If the grass-roots institutions want to give full play to the full strength of professional and technical personnel, it is necessary to do a good job in talent management and incentive work. Now, in order to let the professional and technical talents stay and play their talents, more grass-roots institutions use talent incentive mechanism to reflect the value of talents. However, in reality, the talent incentive mechanism of professional and technical talents still faces many problems in grassroots institutions, such as backward human resource management concept, incomplete talent incentive mechanism system, and low level of organizational culture construction. Based on this situation, this paper thinks that to improve the talent incentive mechanism of professional and technical talents in grassroots institutions, we can start from the following three points: first, to improve the talent incentive mechanism and salary system; second, to update the management concept and improve the evaluation management system; third, to pay attention to the needs of employees and create a harmonious organizational cultural environment.