Today, as globalization continues to strengthen, frequent multilateral trade has triggered a series of competitions and conflicts between countries and regions centered on science and technology. Since 2019, the United States has imposed a series of trade technology sanctions on China's high-tech companies represented by HUAWEI. This article summarizes the impact of HUAWEI through case analysis, collects and integrates its response measures, and analyzes and analyzes the measures for companies to effectively deal with technical barriers to trade in other countries, such as strengthening core technology research, cultivating and introducing high-level talents. Moreover, this work finally concludes that the US technical blockade against China will hardly be effective in the long term, and cooperative development is still the mainstream of the international community.