With the development of network technology, E-commerce has been widely used in many fields, which also provides a lot of convenience for our daily life and work, but it also brings many disputes about intellectual property infringement and damages the legitimate interests of others. In order to better protect intellectual property rights, we need to strengthen intellectual property legislation and law enforcement under the Ecommerce environment, and continuously strengthen the construction of network facilities by using advanced network technology, so as to give full play to the important guiding role of E-commerce in promoting people's social life exchange, shopping, learning and medical treatment.