小型豬血液生理指標檢測

Determination of hematological parameters in miniature pigs

吳昇陽(Sheng-Yang Wu) ； 章嘉潔(Chia-Chieh Chang)

《畜產研究》 51卷1期 (2018/03) Pp. 1-7

摘要

本試驗旨在建立小型豬血液生理指標值的正常參考範圍，並與國內其他小型豬品種血液生理指標進行分析比對，提供小型豬作為人類疾病模式參考依據。利用全自動血液分析儀測定小型豬血液的8項生理指標，對不同性別、月齡及品種的血液測定值進行分析與比較。試驗結果顯示，蘭嶼豬3月齡雌、雄間僅RBC、MCV及MCH等血液生理指標值有顯著差異（P＜0.05），蘭嶼豬6月齡雌、雄間統計，僅MCV、HCT、MCHC及HGB等指標值差異顯著（P＜0.05），其他各項指標雌、雄間均無顯著差異，同性別在蘭嶼豬血液生理指標值3月與6月齡間差異不顯著，其中公畜血液生理指標值MCV、HCT及MCH在3月與6月齡之間呈顯著差異（P＜0.05），母畜血液生理指標值MCHC及HGB在3月與6月齡之間差異顯著（P＜0.05）。另比較不同品種小型豬血液生理指標，結果顯示蘭嶼豬與賓朗豬相比有6項指標值差異顯著（P＜0.05）如WBC、PLT、HCT、MCH、MCHC及HGB，與花斑豬相比有5項指標值如WBC、PLT、MCV、MCH、MCHC及HGB差異顯著（P＜0.05），與迷彩豬相比有5項指標如WBC、MCV、HCT、MCH及HGB差異顯著（P＜0.05）。結果顯示不同品種血液生理指標是有差異，顯示各具獨特的生理特徵。透過血液生理指標測定值比較，以及與人類正常對應參考值、國外著名的哥廷根小型豬和中國實驗用小型豬，及國內賓朗豬、花斑豬、迷彩豬及李宋豬對照，希望對小型豬應用人類醫學研究提供參考依據。

關鍵字

小型豬 ； 生理指標 ； 血液

並列摘要

The aim of this study was aimed to determine the hematological parameters in miniature pigs, so as to provide the basic reference data. Eight hematological parameters in Lanyu pigs were measured using automatic hematological analyzer and the differences between sexes, age, and species were analyzed. The results showed among the hematological parameters, only RBC, MCV and MCH showed significant difference between male and female Lanyu pigs in 3 month (P ＜ 0.05). MCV, HCT, MCHC and HGB showed significant difference between male and female Lanyu pigs in 6 month (P ＜ 0.05).There were no sex differences in the other parameters. The hematological parameters between 3 and 6 month in the same sex were not significantly different. MCV, MCH and HCT showed significant difference between 3 and 6 month in male (P ＜ 0.05). MCHC and HGB showed significant difference between 3 and 6 month in female (P ＜ 0.05). To compare the differences of blood physiological parameters among the Lanyu pigs and Binlang pigs, there were significant differences in WBC, PLT, HCT, MCH, MCHC and HGB (P ＜ 0.05) between the Lanyu minipigs and Spotty Lanyu pigs, there were significant differences in WBC, PLT, MCV and MCH (P ＜ 0.05) and between the Lanyu pigs and Mitsai pigs, there were significant differences in WBC, MCV, HCT, MCH, HCHC and HGB (P ＜ 0.05). Throughout the comparison among the different types of miniature pig breeds and the human reference values, Gottingen minipigs, Chinese experimental minipigs, Binlang pigs, Spotty Lanyu pigs, Mitsai pigs and Leesung pigs the reference could help the use of miniature pigs in medical science research.

並列關鍵字

Miniature pig ； Hematological parameter ； Blood