不同小型豬血液生化值與品種間之差異

Reference values of biochemical parameters among minipigs of difference breeds

吳昇陽(Sheng-Yang Wu) ； 章嘉潔(Chia-Chieh Chang)

《畜產研究》 52卷4期 (2019/12) Pp. 198-205

摘要

本試驗旨在建立蘭嶼豬、賓朗豬、花斑豬和迷彩豬血液生化項目檢測值，並比較血液生化項目之檢測值差異，提供小型豬基礎血液生化檢測值是評估豬隻健康與研究生物醫學中血液學重要的依據。採用全自動生化分析儀，測定3月齡小型豬血液20項生化項目，對檢測資料進行分析與比較。試驗結果顯示，蘭嶼豬與賓朗豬兩組進行比較有14項檢測值呈顯著差異 （P ＜ 0.05），與花斑豬比較有8項檢測值呈顯著差異（P ＜ 0.05），與迷彩豬比較有10項檢測值呈顯著差異（P ＜ 0.05）。蘭嶼豬血液生化檢驗項目處於人類正常參考值範圍中的有10項：AST、ALB、A/G、TP、BUN、CREAT、Mg、Na、Cl及Ca。賓朗豬血液生化檢驗項目處於人類正常參考值範圍中的有7項，花斑豬及迷彩豬血液生化檢驗項目處於人類正常參考值範圍中的有9項。試驗結果顯示蘭嶼豬血液生化檢測值，與人類正常檢驗參考值相比，於20項中有10項相近。雖然這些豬種皆是蘭嶼豬衍生出來的近親品種或合成品種，結果顯示某些特定的血液生化值在不同品種間呈現顯著差異。提供選擇小型豬作為生物醫學研究模式時，亦須考慮品種間血液生化檢驗值的差異。本篇亦進行上述豬種血液生化檢驗值與人類正常參考值、國外著名的哥廷根小型豬及李宋豬品種比較，為建立小型豬生物學特性之資料庫提供依據。

關鍵字

小型豬 ； 生化檢測值 ； 血液

並列摘要

The aim of this study was to compare the differences of blood biochemical parameters among the Lanyu pig, Binlang pig, Spotty Lanyu pig and Mitsai pig. This assay was aimed to determine the blood biochemical parameters, so as to provide the blood reference values for minipigs. Twenty biochemical blood parameters were measured using automatic biochemical analyzer and the differences between different groups were analyzed. Present results showed 14 blood biochemical parameters had significant differences between Lanyu pig and Binlang pig (P ＜ 0.05); While 8 blood biochemical parameters were significant difference between the Lanyu pig and Spotty Lanyu pig (P ＜ 0.05) and 10 indices were significant differences between the Lanyu pig and Mitsai pig (P ＜ 0.05). The results showed these 10 blood biochemical parameters of Lanyu pig were similar to those of human beings, which included AST, ALB, A/G, TP, BUN, CREAT, Mg, Na, Cl and Ca. Seven blood biochemical parameters of Binlang pig were measured in the average range of normal blood biochemical parameters in human reference ranges; 9 blood biochemical parameters in Spotty Lanyu pig and Mitsai pig were closer to those of human. Compared with human beings, 10 of 20 biochemical blood parameters in Lanyu pigs were similar, so it might be more suitable laboratory animals for biomedical researchs. Throughout the comparison of among the four minipig breeds and Göttingen minipig, Leesung pig, as wellas the human, reference values of biochemical parameters those important information could be served as biological characteristics of reference databases.

並列關鍵字

Minipig ； Biochemical parameter ； Blood