In the era of "great science ", the" Declaration on the Construction of New Arts "advocates that the goal of cultivating new liberal arts professionals should be to realize the transformation of single skill to compound type, professional quality to cross and comprehensive quality type. Therefore, the training goal of management discipline in colleges and universities should be changed from specialized talents to compound talents who know both new frontier technology and management. According to the adjustment of training goal, this paper puts forward that the teaching organization structure should be adjusted accordingly. This paper holds that the teaching of ideological and political curriculum group, humanities curriculum group, digital technology curriculum group and management professional subject group can still maintain the existing weak matrix organizational structure, while the cross curriculum group can adopt strong matrix teaching organizational structure to meet the needs of the current national construction for complex talents.