Based on the current situation of College Students' classroom learning, this paper analyzes the factors influencing college students' classroom acquisition by using questionnaire survey and factor analysis, and constructs the index evaluation system of College Students' classroom acquisition. According to the actual investigation and index characteristics, this paper puts forward specific measures to enhance college students' sense of classroom acquisition, which provides practical and theoretical reference for improving college students' sense of classroom acquisition, improving classroom efficiency and stimulating students' interest in learning.