In recent years, studying in Thailand has also become one of the hot choices for Chinese students to study abroad, so the study of the cross-cultural adaptation of Chinese students in Thailand is becoming more and more important, and the number of relevant research is small and basically in the form of questionnaires. In this study takes five Chinese students from A University in Thailand as the research objects, and their cross-cultural adaptation was investigated in depth by way of in-depth interviews in qualitative research. Under the guidance of relevant theories, this study analyzed the current situation of cross-cultural adaptation from different levels of the respondents' daily life and studies, and analyzed and summarized the main factors that affect their cross-cultural adaptation. Finally, this study putted forward some suggestions on how Chinese students in Thailand can better adapt to cross-cultural.