Human resource management changes with the development of society. It is used to realize the scientific allocation of human resources in the organization and to arouse the vigour of enterprises. The implementation of human resource management in universities is quite different from that in enterprises. Rigid management has been dominated in universities, which hinder the development of educational reform. Based on the theoretical research, reviewing the domestic and foreign literature of flexible human resource management, the paper analyses the related concept and features of flexible management, the importance of flexible management in human resource management in colleges and universities and the existing human resource management problems in universities in China, thus propose strategies of applying flexible management concept to human resource management in universities.