低溫電漿處理對Ti-40Nb-1Hf合金之表層微結構之影響研究

The effect of low temperature plasma treatment on the surface characteristics of Ti-40Nb-1Hf alloy

張振庭(Chen-Ting Chang)

指導教授 ： 潘永寧

共同指導教授 ： 歐耿良(Keng-Liang Ou)

國立臺灣大學/工學院/機械工程學研究所/碩士(2006年)

https://doi.org/10.6342/NTU.2006.00935

摘要

鈦及鈦合金因為具有低楊氏係數，良好的降伏強度，優異的腐蝕抗阻及生物相容性，故廣泛應用於生醫設備及元件上。本研究選用具優良機械性質之Ti-40Nb-1Hf合金，探討低溫電漿處理對於表層微結構之影響，並進而探究其生物相容性。X-ray繞射圖譜顯示Ti-40Nb-1Hf合金表層有β相結晶狀組織之氧化層，且β相繞射峰值隨著電漿處理功率的增加而變大。另由XPS分析得知，Ti-40Nb-1Hf合金經由電漿處理後，會提升氧化層中TiO2及Nb2O5之含量，TiO2及Nb2O5具有相當高的抗腐蝕性質，因此預期會有助於提升生物相容性。AFM和接觸角/表面能的分析結果顯示Ti-40Nb-1Hf合金經由電漿處理後，獲得較佳表面粗糙度及接觸角，隨著電漿處理功率增加，表面型貌及表面潤濕性愈佳。於生物相容性研究上，藉由細胞數量分析與母骨細胞生長情形之SEM觀察，顯示Ti-40Nb-1Hf合金經由電漿處理後，細胞活性較未處理者高，故生物相容性亦應有所增進。

關鍵字

Ti-40Nb-1Hf合金 ； 低溫電漿 ； 生物相容性

並列摘要

Titanium and its alloys are widely used in biomedical equipments and components, due to their properties such as relatively lower modulus, good fatigue strength, corrosion resistance and biocompatibility. The aim of this study was to investigate the effect of low temperature plasma treatment on the surface characteristics of Ti-40Nb-1Hf alloy, and further to examine the biocompatibility of the treated alloy. The crystal structure, chemical compositions, surface topographies, wettability as well as cell morphology were investigated by using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), water contact angle measurement and scanning electron microscope (SEM).
The results of XRD analysis indicate that plasma oxidation induces the formation of titanium oxide. Furthermore, the intensity of the β-Ti peak increases with increasing plasma energy. In addition, the XPS data reveal that the rate of TiO2 and Nb2O5 in the oxide layer increases after being O2 plasma treated. Surface properties were studied by the atomic force microscopy (AFM) and contact angle analysis. The results show that as the power of O2 plasma increases, both the surface roughness and water contact angle decrease.
Regarding the biocompatibility, the cell count analysis and SEM observations of the plasma-treated Ti-40Nb-1Hf alloy show that the cell activity of specimens with plasma treatment is better than those without plasma treatment, and hence, the biocompatibility of the Ti-40Nb-1Hf alloy can be expected to improve.

並列關鍵字

Ti-40Nb-1Hf ； low temperature plasma ； biocompatibility

參考文獻

【1】 洪炎輝, 生醫用鈦合金之合金開發及機械性質研究, 國立台灣大學機械工程學研究所博士論文, 2004.

【2】 D. R. Sumner and J. O. Galante: Clin. Orthop. Relat. Res. 274 202-212 (1992).

【7】 Lynch SE, Buser D, Hernandez RA, Weber HP, Stich H, Fox CH, Williams RC. Effects of the platelet-derived growth factor/insulin-like growth factor I combination on bone regeneration around titanium dental implants, results of a pilot study in beagle dogs. J Periodontal, 62: 710-716, 1991.

【9】 Aronsson BO, Lausmaa J, Kasemo B. Glow discharge plasma treatment for surface cleaning and modification of metallic biomaterials. J Biomed Mater Res, 35: 49-73 1997.

【11】 Shibata Y, Miyazaki T. Anode glow discharge plasma treatment enhances calcium phosphate adsorption onto titanium plates. J Dent Res, 81:841-847, 2002.