氣球擴張式血管支架參數化設計與模擬

Parametric Design and Simulation of Balloon-Expandable Stents

王宏達(Hung-Ta Wang)

指導教授 ： 蕭浩明

國立臺灣大學/工學院/機械工程學研究所/碩士(2011年)

https://doi.org/10.6342/NTU.2011.02341

摘要

血管支架應用於治療冠狀動脈窄化成果顯著，使其已成為治療心血管疾病的黃金標準，並廣泛應用於人體其他周邊血管，因此血管支架具備雄厚的成長潛力。以往血管支架研製流程為傳統設計、製成加工、性能測試，由於傳統設計方法十分費時，無法針對測試結果做有效率的修改，為了改善血管支架研製效率，本研究將參數化設計概念(Parametric Design)和有限元素法(Finite Element Method)加入血管支架的研製流程，使研製流程更加有效率，其中有限元素分析用於預測支架性能測試的結果，而經由參數化設計的支架，可針對有限元素分析結果快速的修改局部設計參數，在參數化設計和有限元素法相輔相成的作用下，使血管支架研製效率大幅提升，且降低研發成本。本論文並將參數化設計支架之局部參數做微調，且透過有限元素分析測試其性能的改變，並以圖表方式呈現各式設計參數與支架性能的對應關係，再次驗證參數化設計概念與有限元素法對支架研製流程的重要性。

關鍵字：氣球擴張式血管支架、參數化設計、有限元素分析

關鍵字

氣球擴張式血管支架 ； 參數化設計 ； 有限元素分析

並列摘要

Due to the significant achievement of curing coronary narrowing, stents are widely applied to the other wounded parts of human body or specific medical purposes. Therefore, stents have got abundant developing potential. Stents’ conventional development process is: traditional design, manufacture of processing, performance testing, and FDA certification. Because traditional design method takes much time and can not efficiently do the modification according to the test results, to improve the efficiency of stent development, this research puts parametric design and finite element method into the development process so that the stents’ development process now changes as follows: parametric design, finite element simulation analysis, manufacture of processing, performance testing, and FDA certification. Finite element analysis is used to predict the results of performance testing. And the local design parameters of parametric design stents can be quickly modified according to the test result by finite element analysis. The cooperating between parametric design and finite element method significantly increases the efficiency of stent development and reduces its costs as well. In chapter 5 of this thesis, the local parameters of parametric design stent have been fine -tuned, through finite element analysis, the test of performance changes has been done, and the graph shows the corresponding relationship between various design parameters and stent performance. All of these have once again proven that parametric design and finite element method are important for stent development process.
Keywords : Balloon-Expandable Stent、Parametric Design、Finite Element Analysis

並列關鍵字

Balloon-Expandable Stent ； Parametric Design ； Finite Element Analysis

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