- 學位論文
前庭誘發肌性電位刺激及記錄系統之整合及研製
Vestibular-evoked Myogenic Potential (VEMP) Stimulating and Recording System
摘要
前庭之耳石器官是前庭系統中負責人體之平衡感覺的器官之一，可接受頭部之線性加速度以及傾斜度的刺激，使人可以感受到頭部的空間位置與位置的改變，並作出適當反應。近年來因前庭誘發肌性電位理論的提出，使深藏於內耳深處的耳石器官得以透過表面肌電位的量測，利用非侵入式的方法判定其功能之好壞，進而提供醫師客觀評估耳石器官功能與病變的依據。 本研究之目的即為整合能誘發前庭反應的刺激模式－聲音刺激、機械性刺激(含頭部加速度記錄)、以及電刺激，並根據前庭誘發肌性電位之電位大小及頻譜，研製一具有最佳化規格之放大濾波的四通道記錄系統，以改善市售儀器之功能不敷使用及不易整合的缺點。整套系統以個人電腦為使用平台，透過A/D卡及LabVIEW所開發而成的虛擬儀錶程式連結成一具使用彈性、低價格、低功率消耗並能搭配實驗及研究需求而快速開發的一套刺激記錄系統，作為將來臨床實驗之設備。
並列摘要
The human otolith organs in the inner ear are peripheral sensory apparatuses responsible for the perception of head and body orientation. They respond to both linear head motion and static tilt with respect to gravitational axis. In recent years, the development of vestibular-evoked myogenic potential (VEMP) theory allows clinicians to evaluate the function of otolith organs and otolith-related disorders objectively and non-invasively by means of the recording of myogenic potential elicited by proper stimulation of these organs. The aim of this study is to integrate three kinds of stimulation modes－air conducted sound, bone conducted vibration(with the recording of head acceleration), and galvanic stimulation－and a four-channel recording system optimized for VEMP recording, in replacement of commercial machines inadequate for their function and system integration, was developed. The system is implemented on a personal computer platform through the use of an A/D data acquisition card and a LabVIEW GUI-based virtual instrument. The low-cost, low-power consumption stimulating and recording system is flexible and suitable for future clinical experiments.