高雄市前鎮區、苓雅區(2002)和持續以百滅寧篩選的苓雅篩藥(1990R)品系埃及斑蚊與感性品系的抗性比,成蟲皆大於312.5,於幼蟲則分為20.8、37.5和102.1,故野外品系的蚊蟲抗藥性仍有提升之空間。以WHO的合成除蟲菊酯殺蟲劑藥膜測試2002年台南和高雄埃及斑蚊(Aedes aegypti)成蟲的半數擊昏時間(KT50)和24小時死亡率。高雄巿前鎮區和苓雅區(2002)品系對賽飛寧具抗藥性。高雄巿前鎮區和苓雅區(2002)品系對第滅寧具抗藥性。高雄巿前鎮區、苓雅篩藥(1990R)、苓雅區(2002)和新興區,高雄縣林園鄉和鳳山巿品系對依芬寧具抗藥性。高雄巿前鎮區、苓雅區(2002)、新興區、三民區和左營區,高雄縣林園鄉、岡山鎮和鳳山巿,台南縣歸仁鄉、新巿鄉,和台南巿南區、西區和中區品系對百滅寧產生抗藥性。而高雄巿三民區、左營區和高雄縣岡山鎮品系對賽洛寧具抗藥性。本研究推測埃及斑蚊對百滅寧的抗藥性為2002年南台灣登革熱疫情難以控制的原因之一。2003年高雄市前鎮區、苓雅區和高雄縣鳳山市品系埃及斑蚊對依芬寧和百滅寧仍具抗藥性,但前鎮區和苓雅區對於賽飛寧和第滅寧的抗藥性降低。台南市南區埃及斑蚊對百滅寧和賽洛寧感藥性皆低,為抗藥性較嚴重地區。台南縣歸仁鄉埃及斑蚊對百滅寧和賽洛寧具抗藥性。協力劑測試則顯示埃及斑蚊幼蟲對百滅寧的抗性與氧化
The resistance ratios of adult mosquitoes of the Chianjen, Lingya (2002), and Lingya (1900R) strains for permethrin compared to susceptible strains were above 312.5X, while those of the 4th instar larvae were 20.8, 37.5, and 102.1, respectively. We used WHO insecticide-impregnated papers to determine the insecticide susceptibility of adult Aedes aegypti in 2002.. The Chianjen and Lingya (2002) strains showed resistance to cyfluthrin. The Chianjen, Lingya (2002), and Shinshing strains showed resistance to deltamethrin. The Chianjen, Lingya (1990R), Lingya (2002), Shinshing, Linyuan and Fengshan strains showed resistance to etofenprox. The Chianjen, Lingya (2002), Shinshing, Sanmin, Tzuoying, Linyuan, Gangshan, Fengshan, Gueiren, Shinshi, S. District, W. District, and C. District strains showed resistance to permethrin. The Sanmin, Tzuoying, and Gangshan strains showed resistance to lambdacyhalothrin. 2003, the Chianjen, Linya and Fengshan strains of Aedes aegypti were resistant to both etofenprox and permethrin, but the Chianjen and Lingya (2002) reduced resistance to cyfluthrin and deltamethrin. The Tainan South District strain of Aedes aegypti showed the resistant to permethrin and cyhalothrin. The Tainan Gueiren strain of Aedes aegypti showed the resistant to permethrin and cyhalothrin. Results of a synergism study on larvae resistant to permethrin showed correlations to the activities of microsomal monooxygenases and esterases. The highest specific activities of esterase are 0.249