This study has developed a Nano Composite Materials, made by high polymer material and nano powder materials, which can be used for flexible measure sensor. The high polymer material has the characteristics of soft and flowing ability in colloidal patterns. Moreover, this high polymer material should have the capacity of high load without damage after solidified. The characteristics of flowing ability of the high polymer material can reduce the possible difficulty in the printing process. Therefore, the PDMS high polymer material is used as the substrate materials of sensor. We mix the high polymer material with nano powder in different proportions according to their different characteristics to perform the experimental study. This study has found the suitable composite material for the substrate of pressure sensor. We have also developed the best fabricated process for this printable composite materials and the printing process which can be used in the fabrication of array-type flexible sensor system. Its feasibility has been confirmed through fabricating a prototype.