新式細胞療法應用於特殊奈米表面處理之人工牙根於臨床之整合性分析

Cell therapy of SLAffinity-treated implants enhances the early osseointegration: A clinical analysis

黃永然(Yung-Jan Huang)

指導教授 ： 黃瓊芳

臺北醫學大學/醫學工程學院/醫療器材產業碩士專班/碩士(2017年)

摘要

無資料

關鍵字

人工牙根 ； 細胞療法 ； 奈米處理

並列摘要

The aim of the present study was to examine the early osseointegration of SLAffinity implants when combined with StemBios (SB) cell therapy. The SLAffinity surfaces were characterized using scanning electron microscopy (SEM). For the clinical success of dental implant treatments, it is important to evaluate the magnitude and location of the maximum stresses. Stress analysis was performed using 3-D models constructed using a computer-aided program. Six patients were enrolled in a clinical trial. Each patient received one SLAffinity implant in the mandible. Of these six patients, three received SB cell therapy in addition to the SLAffinity-treated implant. Resonance frequency analysis (RFA) and computed tomography (CT) were performed at 3 time points; 1, 2, and 4 months after implant treatment. Our results indicate that the additional SB cell therapy significantly promotes early osseointegration, especially in the early stages of bone tissue remodeling. SB cell therapy also facilitates efficient stress transfer in SLAffinity dental implants. SLAffinity implants proved to be a clinical success over the 4-month period as well.

並列關鍵字

SB cell therapy ； early osseointegration ； nano/microporous surface treatment ； bone tissue response

參考文獻

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