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  • 學位論文

多孔性導引組織再生膜之生物相容性研究

Research of biocompatibility on permeability guided tissue regeneration membrane

指導教授 : 歐士輔

摘要


導引組織再生膜是為了阻隔牙齦上皮和結締組織之不良影響而達到牙周組織再生的目的。而這些痊癒的過程可由組織學上的研究發現得到證實,當只有牙周韌帶組織細胞與牙根表面接觸時,才能再生具有功能性的牙周韌帶(Functional Periodonium)。有鑑於此,用於導引組織再生術中的再生膜之膜孔、膜厚、膜強度、使用材料的生物相容性等等物化性質便直接地影響導引組織再生術的成功與否。因此,如何精準地控制再生膜的尺寸、結構、物化性質等,便成為製造導引組織再生膜過程中一項重要的課題。

並列摘要


The function of permeability guided tissue regeneration membrane is to enhance tissue regeneration of periodontium by preventing gingival epithelium and connective tissue barrier adverse effect. The healing process can be confirmed by histological studies – regeneration of functional peridonium occurs only as the connection of tissue periodonium to root surface. Pore size, thickness, strength of regeneration membrane, as well as it physical-chemical quality of material (biocompatibility) will affect the successful of guided tissue regeneration directly. So, it become a very important issue to find out a method for controlling the pore size, structure and physical-chemical quality of regeneration membrane.

參考文獻


[24] 郭芳志, 許博智, 陳元武, 張燕清, 夏毅然, 李曉屏. 以具空間維持再生膜閉合長期之口竇相通--病例報告及文獻回顧. 臺灣口腔顎面外科學會雜誌. 2010;21:133-42.
[38] 鄭信忠, 詹宗瑾, 李勝揚, 林哲堂, 歐耿良. 經電化學處理之鈦金屬表面奈米多孔性氧化層之研究. Chin Dent J. 2006;25:96-102.
[1] Bonfield W. Designing porous scaffolds for tissue engineering. Philos T Roy Soc A.2006;364:227-32.
[2] AR Gazdag JL, D Glaser and RA Forster. Alternatives to Autogenous Bone Graft: Efficacy and Indications. J Am Acad Orthop Surg. 1995;3:1-8.
[3] Madihally SV, Matthew HWT. Porous chitosan scaffolds for tissue engineering. Biomaterials. 1999;20:1133-42.

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