飲食中鈣質介入體重控制計畫對於體重過重及肥胖者減重成效之評估

本研究目的主要是探討對於體重過重或肥胖者，給予高鈣低熱量飲食介入體重控制計畫，對於減重成效與體組成之影響，藉以了解在體重控制中提供足夠的鈣質攝取是否能改善體重過重或肥胖者體內脂肪量。本實驗受試者為平日鈣攝取量少於500毫克/天，且健康的體重過重或肥胖者 (BMI：25~30 公斤/(公尺)2) 共42位，隨機且雙盲分成高鈣組 (每日攝取兩份高鈣代餐) 以及控制組，人數各為21人，分別有16位女性及5位男性。兩組提供8週的低熱量飲食 (熱量：1200大卡/天，醣類：55%，脂肪：25%，蛋白質：20%)，並於實驗第0週與第8週進行3日飲食紀錄、體組成以及血液生化值的分析。由飲食分析的結果顯示，在鈣質攝取量的部分，高鈣組實驗後平均鈣質攝取量為964.5 ± 75.5毫克，明顯大於控制組的353.7 ± 96.6毫克 (p<0.05)；減重8週後，兩組在體重、BMI、體脂肪、體脂肪百分比、腰圍、腰臀比、血中總膽固醇、三酸甘油酯、LDL-C濃度、TC/HDL-C的比值均較減重前顯著的下降。此外，高鈣組的體重 (-6.9 ± 3.3 公斤, p<0.05)、BMI (-2.7 ± 1.1公斤/(公尺)2, p<0.01)、體脂肪 (-5.7 ± 2.7 公斤, p<0.05)、體脂肪百分比 (-5.7 ± 2.7 公斤, p<0.05) 以及TC/HDL-C的比值 (-0.4 ± 0.6, p<0.05) 皆比控制組顯著的降低。在血清副甲狀腺素的部分，高鈣組在實驗第8週明顯低於第0週 (p<0.05)，而血清副甲狀腺素的濃度與鈣質的攝取呈現負相關。因此，在限制熱量攝取的減重條件下，給予體重過重或肥胖者足夠的含鈣飲食，可增加體重控制的效益。

關鍵字

肥胖；低熱量飲食；體重控制；減重；鈣質；副甲狀腺素

並列摘要

The purpose of this study was to assess the impacts of dietary calcium intervention on effectiveness of weight loss program in obese. All subjects had an initial BMI (body fat index) >24 kg/m2 and low calcium diet (<500 mg/d). Forty two healthy overweight or obese were randomly and equally divided into two groups: Hi-Ca group (female: 16, male: 5) and control group (female: 16, male: 5). In Hi-Ca group, we provided two bottles of Hi-Ca drinks per day and low energy diet (energy: 1200 kcal, carbohydrate: 55%, fat: 25%, protein: 20%) for 8 weeks. In control group, we only provided low energy diet for 8 weeks. We measured 3-day-food record, anthropometric and blood biochemical data respectively at week 0 and week 8. After 8 weeks, results showed that the calcium intake was 964.5 ± 75.5 mg in Hi-Ca group is where 353.7 ± 96.6 mg in control group (p<0.05). Besides, the loss of body weight (-6.9 ± 3.3 kg, p<0.05), BMI (-2.7 ± 1.1 kg/m2, p<0.01), body fat mass (-5.7 ± 2.7 kg, p<0.05), body fat percentage (-4.4 ± 1.9 %, p<0.002) and TC/HDL-C (-0.4 ± 0.6, p<0.05) in Hi-Ca group were significantly different from those of control group in 8 weeks. In the of lipid profile, serum cholesterol, triglyceride and LDL-C concentration were significantly decreased compared with those in week 0. In the serum PTH (parathyroid hormone) level, Hi-Ca group was significantly lowered compared with the baseline (-5.3 ± 10.4 pg/mL, p<0.05) in week 0, which showed that the concentration of PTH and calcium intake were negative correlation and indicated that using high calcium diet together with low energy diet on weight loss program had more significant decreasing in body weight, BMI, body fat mass, and body fat percentage. Therefore, under the circumstance of energy restricted diet, it would increase the effectiveness on weight loss that giving high calcium diet to those overweight and obese humans.

並列關鍵字

obesity ； energy restricted diet ； weight loss ； calcium ； parathyroid hormone (PTH)

參考文獻

Ahlström T, Hagström E, Larsson A, Rudberg C, Lind L, Hellman P. Correlation between plasma calcium, parathyroid hormone (PTH) and the metabolic syndrome (MetS) in a community-based cohort of men and women. Clin Endocrinol. 2009; 71: 673-8.

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飲食中鈣質介入體重控制計畫對於體重過重及肥胖者減重成效之評估

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