經陰極及陽極電化學處理之鈦金屬植體表面奈米多孔性氧化層研究

諸多研究顯示，鈦基金屬及其合金於人體的生物相容性(biocompatibility)有極高的評價，其非常適合做為人體的植入物，然而鈦金屬及其合金之所以具極佳的生物相容性主要是與鈦金屬表面的氧化層有關，且於一些研究及文獻亦顯示植入生物體內材料表面的孔徑大小和細胞初始的攀附行為、增殖及分化有密切的關係。若能有效控制氧化層為網狀奈米多孔性將對骨整合會有所助益。因此，本研究以電化學陰極處理方式使鈦基金屬表層形成一層氫化鈦(TiH2)薄膜，再以電化學陽極處理，使表面形成一層網狀奈米多孔性的二氧化鈦(TiO2)結構，並以一些物理化學性的分析儀器測試表面之成分、元素、膜厚、孔洞大小及結構，並探討網狀奈米多孔性的二氧化鈦的形成機制。根據本研究結果顯示，以一般傳統陽極處理方式，若氧化層厚則孔徑相對較大，若要使氧化層更厚孔徑更小，則氫化鈦是形成氧化層更厚之網狀奈米多孔性結構主要因子，因為氫化鈦為奈米相，當氫化鈦溶於鹼液中而形成溶解反應，而形成更厚之網狀奈米多孔性結構二氧化鈦。

關鍵字

陰極處理、陽極處理、網狀奈米多孔性二氧化鈦

並列摘要

Titanium-based alloys with excellent biocompatibility have been investigated by many researches. It is due to its passive oxide film. The surface characteristics of titanium implant, such as pore sizes/roughness, are related to initial cell behaviors and osseointegration. It seems to be helpful to osseointegration if can effectively keep the oxidation in nanoporous. However, the surface design of dental implant for enhancing the rate and result of osseointegration remains unknown. In this study, electrochemistry process was performed as surface treatment of titanium-based implant. Titanium hydride (TiH2) was formed on titanium implant surface after cathode treatment. Nanoporous titanium oxide structure was formed by anodic surface treatment. As the mention above, physical properties, chemical properties as well as biocompatibility of titanium implant with and without electrochemical surface treatments were analyzed clearly. Furthermore, mechanism of bone healing on nanoporous implant surface and interaction were also discussed clearly. In traditional anodic treatments, the pore size increases with the oxidation thickness.To based on this study, in order to get the thick oxidation and the minimum pore size, the titanium hydride is the main factor in forming thick nanoporous titanium oxide structure. Since the titanium hydride is nano phase structure, when it dissolved in alkaline solution, the more thickness mesh-nanoporous titanium oxidation will be formed.

並列關鍵字

cathode, anodic, mesh-nanoporous titanium oxidation

參考文獻

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經陰極及陽極電化學處理之鈦金屬植體表面奈米多孔性氧化層研究

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