The main purpose of this thesis is to find the realizability of customer relationship management for the health medical institution. Since the culture、vision and industry features of health medical institutes are quite different from the enterprise, the patients-centering shall the core value of customer relationship management of health medical institutions. In practice, recently CRM of health care emphasizes the accessibility、safety、integrity、suitability、participation and continuity of medical care to follow the patient-centered concept. Moreover, this research also adopts the case study for some large hospital to conclude the practices of health care management.