微循環被視為循微系統中最基礎及最重要的部分,而血管的叢集處—穴道,其血流特性是診療上的關鍵點。本研究希望對穴道及週遭兩非穴道在微循環血流的特性上做探討,在此透過局部加熱及針刺激嘗試著改善微循環,並配合非侵入式的雷射都普勒及心電圖對微循環平均血流量及血流波形做初步分析。 在實驗分析上,針對以下七點去做探討:(1) 平均血流量 (2) 血流波形面積 (3) 心跳變異率 (4) 血流波形振幅變異率 (5) 血流波形寬度 (6) 血流波形延遲時間 (7) 血流波形上升時間。經由分析結果,局部加熱導致加熱區域微循環血流量上升,血液灌流增加,微循環變好。在針刺激及局部加熱後,平均血流量、血流波形面積、血流波形振幅變異率及血流波形寬度造成合谷及非穴道有顯著的差異。藉由上述的指標,得到此兩種刺激皆有助於改善微循環血流及找出穴道的特性。未來結合其他非侵入式評估方式,將有助於循環系統的了解及運用於遠距醫療。
Microcirculation is regarded as the most important and fundamental part of circulation system. Acupuncture point, the cluster of blood vessels, is suggested to play key role in treatment. The aim of our study is to improve the blood flow of microcirculation and to compare the characteristics of blood flux between acupoints and non-acupoints. We used two kinds of stimulation—local heating and acupuncture to change the blood flow of microcirculation and measured by non-invasive Laser Doppler Flowmetry (LDF) and Electrocardiogram (ECG). In the analysis ,we focused on the following seven parameters: (1) Average blood flow (DCflux) (2) Area of blood flow pulse (ACflux) (3) Coefficient of Heart rate variation (HR_CV) (4) Coefficient of blood flow pulse amplitude variation (Amp_CV) (5) Pulse width (PW) (6) Foot delay time (FDT) (7) Flow raising time (FRT). Based on the result, local heating increases the blood flow of regional circulation. Acupoints and non-acupoints have significant differences on DCflux、ACfux、Amp_CV and PW compared to baseline values either by acupuncture or local heating. These two kinds of stimulation can help to improve the blood flow of microcirculation and to discriminate the characteristic of acupoints. It could help us to develop measurement index on device to improve the microcirculation.