- 學位論文
A CLINICO-MICRO BIOLOGICAL AND SURGICAL TREATMENT OF INFECTED DIABETIC FOOT ULCER: A RETROSPECTIVE REVIEW OF 517 CASES.
A CLINICO-MICRO BIOLOGICAL AND SURGICAL TREATMENT OF INFECTED DIABETIC FOOT ULCER: A RETROSPECTIVE REVIEW OF 517 CASES.
並列摘要
ABSTRACTS Background: Foot infections are a common, complex and costly complication of diabetes. Twenty-five percent of all diabetes patients develop a foot ulcer at some point in their lives that is highly susceptible to infection and that spreads quite rapidly, leading to overwhelming tissue destruction and subsequent amputation. The aim of our study is to determine the typical presentation, microbiology study and treatment of diabetic foot infection at Kaohsiung Medical University Hospital Material and methods: The medical charts of diabetic patients with infected ulcers admitted at Kaohsiung Medical University Hospital from January 2002 to December 2009 were reviewed. Five hundred and seventeen cases were included. The demographic data was collected, culture results, antibiotics received and types of treatments were analysed Results: Males were 60% of the cases and 80% were over 40yrs with about 26% more than 60yrs. Sixty-five percent had grade II ulcers with 38% on their toes. Hypertension, neuropathy and peripheral artery occlusive disorders were commonest co-morbidity in patients. Gram positive aerobes were the most common isolates. Staph aureus is most common isolate with antibiotic resistant staph aureus constituting 6%. Proteus was the most common gram negative and bacteroides most common anaerobe. Most had debridement of the ulcer and prevalence of amputation was 29%. Fourteen percent had received two or more antibiotics combination during treatment Conclusions: Staph aureus is most common isolate with antibiotic resistant staph aureus constituting 6%. Proteus was the most common gram negative and bacteroides most common anaerobe. Most had debridement of the ulcer and prevalence of amputation was 29%. Most common antibiotic used was ampicillin/salbactam