With the trend of business globalization, expatriate have become a significant part of globalized management. This research aims to investigate the relationship of Social Support and Job Performance in six factories of LingYih Group, which are manufacturing shoes in Vietnam, Myanmar and China. Also examining the mediating effects of Organizational Commitment on the relationship between two constructs of Social Support and Job Performance. Specifically, we propose that Cultural Distance moderate the expatriate between Social Support and Organizational Commitment; Social Support and Job Performance; Organizational Commitment and Job Performance. The survey method was adopted in this study. A total of 297 questionnaires were distributed and 273 copies returned. Among returned questionnaires, 258 copies were valid, with effective return rate of 94.50%. The data were analyzed with regression analysis, hierarchical regression and ANOVA to discuss the relationships among Social Support, Organizational Commitment and Job Performance. The results indicated that Social Support had positive effects on Job Performance and Organizational Commitment had positive effects on Job Performance; Organizational Commitment appears partial mediating effects on the relationship between Social Support and Job Performance. However, culture distance had no significant moderating effect on Social Support and Organizational Commitment, Social Support and Job Performance, and Organizational Commitment and Job Performance.