排尿時之脈波與自主神經系統關係之探討

Investigation of the Relationship between the Pulse Wave and Autonomic Nervous System during Micturition

周家駒(Chia-Chu Chou)

指導教授 ： 張翔

國立清華大學/電機資訊學院/電機工程學系/碩士(2008年)

摘要

本研究主要是探討人體排尿前後，其脈搏強度、波形、心率、心率變異度(Heart Rate Variability)、分形維度(fractal dimension)以及差分分形維度的動態變化，並探討其和自主神經系統的關係。
由以往的實驗指出，小白鼠在進行排尿行為時，其和自律神經系統有相當密切的關係。然而，人體自律神經系統和排尿行為的關係卻尚無任何研究報告。故本論文主要就是探討人體自律神經系統在排尿時所產生的調節機制，並期望在人體的生理訊號中發現能夠代表自律神經系統調節作用的變化和指標。
本實驗的實驗對象共六位，總共進行了二十三次實驗。每次實驗實驗對象都保持一定的姿勢以避免外界干擾被引入實驗數據之中。實驗結果發現，排尿前後實驗者的脈壓、脈波波形、脈波分形維度及差分脈波分形維度皆有明顯的變化。
在本篇論文中，我們經由分析脈波波形及心律得到以下結果：
一、脈波在排尿時會呈現劇烈的振動，而在排尿前後並無太大差異。
二、橈動脈脈波的頻譜在排尿前後，主要的活動集中在較高頻帶 (0.15-0.4Hz)和較低頻帶 (0.04-0.15Hz)。在排尿期間，較高頻帶的強度減弱，較低頻帶的強度上升。而足背動脈則是在排尿前後，其在較低或較高頻帶有一強烈主頻，但在排尿時這主頻之頻率會降低。
三、脈波的分形維度在排尿期間會下降，有些時候會呈現一個W形。
四、脈波的差分分形維度在排尿期間會上升。
五、心率和心率變異度在排尿時並無明顯差異。
未來，我們將會分析這些生理現象的意義，並探討其和自律神經系統的關係。

關鍵字

排尿 ； 脈波 ； 頻譜 ； 分形維度 ； 差分分形維度 ； 心率 ； 心率變異度

並列摘要

The objective of this research is to investigate the relationships between the autonomic nervous system and the pulse waves during micturition. The topic includes the dynamic changes of pulse wave signals, fractal dimension of pulse wave signals, differentiated fractal dimension of pulse wave signals, HR, and HRV. Six healthy volunteers with no neurological conditions participated in this study. A total of 23 trials were obtained before, during and after micturition. In order to minimize artifacts, all experimental subjects remained still during the experiments. The results of the experiments are as follows:
(1) The time-series signals of pulse waves oscillate during micturition.
(2) The major frequency of radial arterial pulse waves are centralized in LF (0.04-0.15Hz) and/or HF (0.15-0.4Hz) bands before and after micturition. During micturition, the major activities of the frequency are in the LF band. And the major activities of frequencies of dorsal pedis artery are in HF and/or LF bands before and after micturition. During micturition, the major activities of the frequency are still in LF band. However, the main frequency band is centered around 0.025-0.05Hz.
(3) During the micturition, the fractal dimension would decrease. Some of them even presented a “W” shape.
(4) The differentiated fractal dimension of the radial arterial pulse waves increased during the micturition.
(5) There is no obvious change in HR and HRV signals during micturition.
We will analyze the physiological signals and investigate the relationships between these signals and autonomic nervous system.

並列關鍵字

Micturition ； pulse waves ； power spectrum ； fractal dimension ； differentiated fractal dimension ； heart rate ； heart rate variability

參考文獻

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