In this study, the vector form intrinsic finite element (VFIFE) method is applied to simulate the geometrically nonlinear behaviors of plane frame structures. Different from the conventional finite element method which is based on the variational theory, the VFIFE method models the analyzed domain to be composed by finite particles and Newton’s second law is applied to describe each particle’s motion. Thus, the calculation of VFIFE method becomes solving a set of uncoupled vector form equations. In the analysis of VFIFE method, the co-rotational coordinate system is used to separate the rigid body motion and pure deformation of the system. After combining it with explicit time integration scheme, the VFIFE method can effectively simulate the dynamic behaviors of multi-bodies system having large deformation. Numerical examples demonstrate that this newly proposed method has quite good accuracy and efficiency on analyses of plane frame structures with large deformation.