本論文以紅光及紅外光之雙波長光學檢測系統,即時量測血氧訊號;同時以精簡設計之生理電訊號檢測系統,即時量測同步心電圖訊號;並以此整合性之即時心電訊號及血氧訊號,深入分析心血管生理參數。研究之實際量測系統以三通道之數位電子設計系統,進行實際人體檢測及驗證。 研究中,系統同時測量三通道生理訊號,其中心電訊號可獲得每位受測者之心律跳動(HR),及心臟活動狀況、紅外光光體積描記圖與紅光光體積描記圖可獲得血氧濃度(SaO2)、紅外光光體積描記圖結合心電訊號可獲得脈波傳導速度(PWV)、紅外光光體積描記圖可獲得血管硬化指數(SI)、血管阻塞指數(RI)等資料,其中之HR、PWV、SI、RI可進行心血管生理狀況評估,SaO2可進行心肺功能,血液氧分含量評估。 本論文依據量測系統擷取訊號後,各項參數之統計資料,可推論受測者之年齡與心血管生理有對應關係之現象,且同時比較穿透式與反射式之差異時發現其各項參數結果之相關度皆可達0.95以上,初步證實反射式光體積描記圖於心血管參數應用之可行性。 本論文以整合光量測與電學分析的一體解決方案(Total Solution),達到心血管功能居家自我監測的應用,並且量測機制簡便,所以於居家儀器中極具發展潛力。
The aim of this study is to design and develop a simultaneous measuring SaO2 and ECG system based on double wavelength-infrared and red light optic system and simple physiological electric signal detection device. This system could measure real-time SaO2 signal and ECG signal simultaneously. When combine with SaO2 signal and ECG signal, we can go deep to analyze cardiovascular parameters. In this study, we use three channel signal-- Infrared PPG, Red PPG and ECG signals to obtain every subject’s Heart Rate (HR), SaO2,Pulse Wave velocity (PWV), vascular stiffness index (SI), vascular reflection index (RI). Through HR, PWV, SI and RI parameter, we can estimate cardiovascular conditions. With SaO2 parameter, we can estimate cardiopulmonary function. The study also discussed the relationships between age and cardiovascular physiology functions based on statistics. This paper brings up the total solution of integrating optical measurements with electrical analysis to achieve the goal of home cardiovascular function monitoring. The development of this system has great potential in home care.