印度油菊化學成分之研究

Phytochemical Studies on the Consitituents of Guizotia abyssinica

張珀豪(Po-Hao Chang)

指導教授 ： 陳建志 ； 謝博進

中原大學/理學院/化學研究所/碩士(2006年)

https://doi.org/10.6840/cycu200600039

摘要

印度油菊，原產於印度，學名 Guizotia abyssinica (L.f.) Cass. ，為翠菊科 (Asteraceae) 油菊屬 (Guizotia) 植物，別名Niger，其種子含多量的油酸。本植物之地上部經甲醇抽取，其甲醇抽出物之水可溶部分經各種色層分析法的分離，共得到四個新的化合物 : 3,2’,4'-trihydroxy-4,3'-dimethoxychalcone (1) 、 abyssinone A (12) 、abyssinone B (13) 及 abyssinal (16) 以及二十五個已知化合物isoliquitigenin (2) 、okanin (3)、butein (4)、quercetin (5)、(–)-liquiritigenin (6)、(–)-7,3',4'-trihydroxyflavanone (7)、(–)-7,8,3',4'-tetrahydroxyflavanone (8) 、7,3',4'-trihydroxyflavone (9)、3,6-dihydroxy-1-menthene (10)、3-hydroxycarvotagenone (11)、ovatifolin acetate (14)、14-acetoxy-8-hydroxycostunolide (15)、ferulic acid (17)、caffeic acid (18)、p-hydroxybenzoic acid (19)、p-coumaric acid (20)、(Z)-p-hydroxycinnamic acid (21)、syringic acid (22)、vanillic acid (23) 、vanillin (24) 、caffeic acid methyl ester (25) 、scopoletin (26)、esculetin (27) 、(+)-pinoresinol (28)及methyl 3,5-dicaffeoylquinate (29)。這些化合物皆以質譜及核磁共振光譜的解析而確認。

關鍵字

藥物研究 ； 印度油菊

並列摘要

Guizotia abyssinica is primarily cultivated in India and its seeds have high content of linoleic acid. The MeOH extract of the aerial part of G. abyssinica was separated into water-soluble and water-insoluble portions. The water-soluble portion was successively chromatographed using Diaion HP-20, silica gel and Sephadex LH-20 to obtain four new compounds：3,2',4'-trihydroxy-4,3'-dimethoxychalcone (1) , abyssinone A (12) , abyssinone B (13) , and abyssinal (16), and together with twenty-five known compounds：isoliquitigenin (2), okanin (3), butein (4), quercetin (5), (–)-liquiritigenin (6), (–)-7,3',4'-trihydroxyflavanone (7), (–)-7,8,3',4'-tetrahydroxyflavanone (8), 7,3',4'-trihtdroxyflavone (9), 3,6-dihydroxy-1-menthene (10), 3-hydroxycarvotagenone (11), ovatifolin acetate (14), 14-acetoxy-8-hydroxycostunolide (15), ferulic acid (17), caffeic acid (18), p-hydroxybenzoic acid (19), p-coumaric acid (20), (Z)-p-hydroxycinnamic acid (21), syringic acid (22), vanillic acid (23), vanillin (24), caffeic acid methyl ester (25), scopoletin (26), esculetin (27), (+)-pinoresinol (28), and methyl 3,5-dicaffeoylquinate (29). These twenty-nine compounds were elucidated by mass and NMR spectral data.

並列關鍵字

phytochemical studies ； guizotia abyssinica

參考文獻

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(11)C. Zdero, F. Bohlmann, R. M. King and H. Robinson, Phytochemistry, 30(5), 1579-1584, 1991