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  • 學位論文

在斑馬魚超量表現Notch訊息會增加成骨作用造成骨質增厚及利用斑馬魚篩選與評價骨合成和分解的化合物

Forced expression of Notch signaling induces osteogenesis and hyperosteogeny in zebrafish Screen and evaluation of bone anabolic and cata bolic compounds in zebrafish

指導教授 : 蕭崇德

摘要


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並列摘要


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並列關鍵字

Drug screen Notch signal Osteosclerosis

參考文獻


2. Hall BK, Miyake T (1992) The membranous skeleton: the role of cell condensations in vertebrate skeletogenesis. Anat Embryol (Berl) 186: 107-124.
3. Erlebacher A, Filvaroff EH, Gitelman SE, Derynck R (1995) Toward a molecular understanding of skeletal development. Cell 80: 371-378.
4. Aubin JE (1998) Advances in the osteoblast lineage. Biochem Cell Biol 76: 899-910.
5. Karsenty G (1999) The genetic transformation of bone biology. Genes Dev 13: 3037-3051.
6. Christ B, Huang R, Scaal M (2004) Formation and differentiation of the avian sclerotome. Anat Embryol (Berl) 208: 333-350.

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