螢光奈米金團簇之創新製備方法

A Novel Method for Direct Synthesis of Fluorescence Gold Nanoclusters

柯承志(Cherng-Jyh Ke)

指導教授 ： 張恒雄

中原大學/工學院/生物醫學工程學系/碩士(2008年)

https://doi.org/10.6840/cycu200900602

摘要

本研究發展一具有螢光特性的金奈米團簇之創新製備方法，並利用質譜儀、EDX、AFM來鑑定金奈米團簇組成之變化。此製備方法具有製程方法簡易、低成本、低環境毒性、可大量生產等能力。其中，上述之金奈米團簇具有不錯的量子產率，且無光漂白，反而有光增強的效應。並與傳統螢光染劑相較算出其量子產率約在10%-20%之間。對於未來應用於生物標定、或者太陽能電池的發展，有極高的潜力。

關鍵字

奈米金團簇 ； 螢光

並列摘要

In this study, a novel method had been developed for synthesis of fluorescent gold nanoclusters. The fluorescent characteristics of this gold nanoclusters were determined based on their absorption and photoluminescence spectrum by using the fluorospectrometer. It suggested that these fluorescent gold nanoclusters may have the potential being an alternative probe against the traditional bio-toxic CdSe quantum dots for the application of labeling, targeting, and imaging in biomedicine.

並列關鍵字

gold nanoclusters ； Fluorescence

參考文獻

61. Jia-Min Shieh, Y.-F. L., Yong-Chang Lin, and Jr-Yau Fang, Photoluminescence: Principles, Structure, and Applications. 奈米通訊 12, (2), p28-39.

62. 蔡有光, 質譜儀技術於蛋白質體分析之應用. 永進生物科技股份有限公司 6, p233-248.

2. Daniel, M. C.; Astruc, D., Gold Nanoparticles: Assembly, Supramolecular Chemistry, Quantum-Size-Related Properties, and Applications toward Biology, Catalysis, and Nanotechnology. In 2004; Vol. 104, pp 293-346.

3. Salama, T. M.; Ohnishi, R.; Shido, T.; Ichikawa, M., Highly Selective Catalytic Reduction of NO by H2over Au0and Au(I) Impregnated in NaY Zeolite Catalysts. Journal of Catalysis 1996, 162, (2), 169-178.

4. Storhoff, J. J.; Elghanian, R.; Mucic, R. C.; Mirkin, C. A.; Letsinger, R. L., One-Pot Colorimetric Differentiation of Polynucleotides with Single Base Imperfections Using Gold Nanoparticle Probes. In 1998; Vol. 120, pp 1959-1964.