電活性蠶絲複合水膠開發與其機械性質和電致變色之研究

Highly-conductive silk fibroin hydrogels: mechanical property and electrochromism study

李冠霆(Guan-Ting Li)

指導教授 ： 楊大毅

中原大學/工學院/化學工程研究所/碩士(2020年)

https://doi.org/10.6840/cycu202000409

摘要

導電水凝膠可被應用於穿戴式電子裝置，以及生物體電極之組裝零組件上，原因在於:其可以取代原本的電線，讓電子產品更具有可撓性和發展性。此外，導電水凝膠可和人體更加緊密接觸，有助於提高人體監測精準度。
本研究利用聚(3,4-乙烯二氧噻吩)-聚苯乙烯磺酸(PEDOT:PSS)導電高分子和苯胺四聚體(Tetra-aniline)導電聚合物，透過直接加入或擴散的方法，使其與蠶絲之絲素蛋白結合，成功製備出高導電度的複合水凝膠。導電測試結果顯示PEDOT: PSS高分子，可將絲素蛋白水凝膠的電阻值降至近10, 000歐姆。再透過流變儀測量發現:PEDOT:PSS可提升絲素蛋白水凝膠之儲存模數；並且縮短水凝膠的交聯時間，而所製備出之水凝膠仍保有PEDOT:PSS高分子之電活性。
再者，苯胺四聚體可藉由擴散方式，進入絲素蛋白水凝膠，而形成苯胺四聚體/絲素蛋白水凝膠。透過循環伏安法可以觀察出: 苯胺四聚體/絲素蛋白水凝膠在高電壓時，其顏色會變成藍色; 而在低電壓時，顏色轉變為綠色，並且保有苯胺四聚體的氧化還原特徵。此外，在鹼性環境中，其顏色為藍色，而在酸性環境下，顏色轉變成綠色。並且，綠色的苯胺四聚體/絲素蛋白水凝膠，具有傳導電流的能力，能使發光二極體發亮。

關鍵字

絲素蛋白 ； PEDOT:PSS ； 苯胺四聚體 ； 導電水凝膠 ； 電致變色

並列摘要

Conductive hydrogels have been gradually enlarged with the development of wearable electronic devices. The reason is that the conductive hydrogels can replace the original wires, so that electronic products can be more flexible and developable. The close contact between the conductive hydrogel and the human body helps to improve the accuracy of human body monitoring.
In this experiment, a high-conductivity hydrogel was successfully synthesized. Poly(3,4-ethylenedioxythiophene) /poly(styrenesulfonate)(PEDOT:PSS) conductive polymer and tetra-aniline(TA) conductive oligomer were utilized to incorporate with silk fibroin to obtain high-conductivity composite hydrogels. The experimental data show that the PEDOT:PSS conductive polymer can lower the composite hydrogel’s resistance to 10,000 ohms. Moreover, the PEDOT:PSS can not only shorten the crosslinking time of the hydrogels, but also improve the storage modulus of the hydrogels, which still have the electroactivity from PEDOT:PSS polymer.
Furthermore, the TA can diffuse into silk fibroin hydrogels to form electroactive composite hydrogels. Cyclic voltammetry analysis shows that the resultant hydrogel still have redox characteristics of tetra-aniline with blue color at higher voltage and green color at lower voltage. In addition, the TA composite hydrogels show blue and green colors as they are in an alkaline and acidic environments, respectively. When the color of TA composite hydrogels is green, they can conduct the electrical current and thus to light up LEDs.

並列關鍵字

silk fiborin ； PEDOT:PSS ； tetra-aniline ； conductive hydrogel ； electrochromism

參考文獻

參考文獻

1 Yuk, H., Lu, B. Zhao, X. Hydrogel bioelectronics. Chemical Society Reviews 48, 1642-1667 (2019).

2 Han, L. et al. Transparent, adhesive, and conductive hydrogel for soft bioelectronics based on light-transmitting polydopamine-doped polypyrrole nanofibrils. Chemistry of Materials 30, 5561-5572 (2018).

3 Nagamine, K., Chihara, S., Kai, H., Kaji, H. Nishizawa, M. Totally shape-conformable electrode/hydrogel composite for on-skin electrophysiological measurements. Sensors and Actuators B: Chemical 237, 49-53 (2016).

4 Qu, J., Zhao, X., Ma, P. X. Guo, B. Injectable antibacterial conductive hydrogels with dual response to an electric field and pH for localized “smart” drug release. Acta biomaterialia 72, 55-69 (2018).