中藥塗佈電漿改質聚丙烯不織布之抑菌活性探討

Investigation of Antimicrobial Activities of Plasma Modified Polypropylene Filter Coated with Chinese Herb Extracts

林振宏(Jhen-Hong Lin)

指導教授 ： 王雅玢 ； 蔡政賢

中原大學/工學院/土木工程研究所/碩士(2011年)

https://doi.org/10.6840/cycu201100926

摘要

近年來，中藥以及天然植物萃取的抗菌成份，相對於一些化學抗菌物質，因較無副作用，對環境也較無危害性而漸受矚目。本研究利用高週波低溫氧電漿改質聚丙烯 (Polypropylene, PP) 不織布，塗佈抗菌藥材防風的酒精萃取物，進行抑菌實驗的測試。
電漿改質條件為O2流量5 sccm，壓力0.09 torr，功率40 W，改質30 sec，結果顯示：提高電漿功率與延長改質時間，均可提高塗佈率與PP親水性，防風塗佈率由未改質的8.2%增加至18.9%。
抑菌實驗顯示，防風萃取物塗佈量越高抑菌效果越好。 滴菌24 hr後洗菌之抑菌實驗顯示：改質PP於超音波震盪脫附三次後之防風塗佈率為27%時，金黃色葡萄球菌之抑菌率達75%；當塗佈率下降至10.3%時，抑菌率降低至61%。
以腔體模擬過濾系統之結果顯示：過濾時間增加，提高濾材靜置時間仍可達到100%抑菌之效果。 對大腸桿菌而言，改質PP (40 W, 30 sec, 塗佈率22.9%) 的過濾效率44%，略高於未改質的35%，且改質PP在5 min的短時間過濾後，靜置 30 min即可達100%的抑菌效率；至於在過濾30 min後靜置480 min與靜置0 min比較，改質PP的抑菌效率達67%，高於未改質PP的33%。 枯草桿菌孢子的測試結果顯示：在相同過濾時間下，改質PP的過濾效率略低於未改質PP，但抑菌效率差異不大，在過濾30 min後靜置120 min之抑菌效率即達97%，可能因未改質PP具有靜電力，對枯草桿菌孢子具較佳之攔截效率有關。
總結：以高週波低溫氧電漿改質聚丙烯不織布濾材，可以提高防風萃取物塗佈率，有效抑制大腸桿菌與枯草桿菌孢子之生物氣膠生長，且抑制枯草桿菌孢子之效果比大腸桿菌略佳，因此防風塗佈之改質PP應有應用於高濃度生物氣膠環境中抑菌之潛力。

關鍵字

聚丙烯 ； 防風 ； 抑菌活性 ； 萃取物 ； 表面改質 ； 高週波電漿

並列摘要

The antibacterial compounds extracted from Chinese herbs and natural plants revealed no side effects, no environmental hazard on human beings. More and more research are processed recently to study the antibiotic effect of Chinese herbs extracts. In this study, polypropylene (PP) non-woven filter was modified by an oxygen-based RF plasma and was coated by the extract of Saposhnikovia Divaricate to evaluate the inhibition efficiency of bioaerosols.
The coating rate will be elevated as increasing applied power and extended modification time. When PP was modified at the conditions: 5 sccm of O2, 0.09 torr of pressure, 40 W of power, and 30 seconds of modification, the coating rate of Divaricate Saposhnikovia root extract increased from 8.2% for unmodified PP to 18.9% for modified PP.
Higher coating rate will lead to higher antibacterial effects. The coating rate is 27% and the inhibition efficiency of Staphylococcus aureus reaches 75% after three times desorption by ultrasonic shaking. The inhibition efficiency of Staphylococcus aureus reduced to 61% while the coating rate decreased to 10.3%.
The results of the pilot test showed that after a longer filtration time, the antibacterial efficiency could be almost 100% by elevating the still duration. The filtration efficiency of E coli was 44% for modified PP (under 40 W, 30 sec, 22.9% of coating rate), higher than 33% for unmodified PP. The persistent inhibition efficiency of E.coli on modified PP for 30 min still duration after 5 min filtration was near 100%. After 30 min filtration, the inhibition efficiency of E.coli on modified PP was 67% for 480 min still duration, higher than that for 0 min still duration (33%). However, the inhibition efficiency of Bacillus subtilis spores was similar between modified and unmodified PP owing to PP’s static electricity on unmodified PP leading to higher filtration efficiency than modified PP. The inhibition efficiency of acillus subtilis spores on modified PP for 120 min still duration after 30 min filtration was above 97%.
This study proved that not only the coating rate of Divaricate Saposhnikovia root extract was improved, but also the inhibition efficiency of bioaerosols was elevated by modifying PP in an oxygen-based RF plasma environment. More, the test result of Divaricate Saposhnikovia root extract coated PP further implied its potential application on indoor air quality improvement.

並列關鍵字

Radio-frequency plasma ； Saposhnikovia Divaricate ； Extract ； Antibacterial efficiency ； Polypropylene ； Surface modification

參考文獻

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